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Cat No. | Product Name | Synonyms | Targets |
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T3614 | Inosine pranobex | Groprinosin,Isoprinosine,Immunovir,Delimmun | IL Receptor , HIV Protease |
Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a... | |||
T26895 | BRD0476 | BRD-0476,ML 187,ML187,ML-187,BRD 0476 | |
BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell ... | |||
T70394 | Deucravacitinib HCl | ||
Deucravacitinib HCl is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bo... | |||
T70291 | PCC0208018 | ||
PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programm... | |||
T10065 | 2',3'-cGAMP | 2'-3'-cyclic GMP-AMP | STING , cGAS |
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP binds to STING to form a dimer, inducing the produc... | |||
T75086 | Dazostinag | ||
Dazostinag (TAK-676 free base) functions as a stimulator of interferon genes (STING) protein agonist, exhibiting antineoplastic properties. It also acts as a payload for the synthesis of antibody-drug conjugates (ADCs) [... | |||
T73696 | Peginterferon alfa-2b | ||
Peginterferon alfa-2b (Sch 54031), a recombinant alfa-2b interferon covalently bonded to polyethylene glycol (PEG), acts as an immunomodulator. This compound is effective in reducing viral DNA in HIV and has potential ap... | |||
T76943 | Cepeginterferon alfa-2b | ||
Cepeginterferon alfa-2b, a pegylated interferon, features a polyethylene glycol (PEG) base with a molecular weight of 20 kDa. This compound is utilized in the research of numerous diseases, including hepatitis C virus (H... | |||
T38320 | 93-O17S | 93-O17S | |
93-O17S is a chalcogen-containing cationic lipidoid.1It has been used in the synthesis of lipid nanoparticles (LPNs) for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice. LPNs containing ... | |||
T35422 | 5'-pApA (sodium salt) | ||
5'-pApA is a linearized form of cyclic di-AMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).1,2,3,4It is a metabolite of cyclic di-AMP formedvia... | |||
T75090 | STING agonist-22 | ||
STING Agonist-22 (CF501) is a potent non-nucleotide STING agonist that functions as an adjuvant by activating STING to induce the type I interferon (IFN-I) response and the production of proinflammatory cytokines. It enh... | |||
T74693 | CDN-A | ||
CDN-A, a cyclic di-nucleotide, serves as a precursor for synthesizing antibody-drug conjugates (ADC) and acts as a potent stimulator of both innate and adaptive immune responses. In humans, these cyclic di-nucleotides, p... | |||
T23028 | MRT67307 HCl (1190378-57-4 free base) | MRT67307 HCl | Others |
MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it i... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10065L | 2',3'-cGAMP sodium | 2'-3'-cyclic GMP-AMP sodium | STING , cGAS |
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP sodium binds to STING to form a dimer... | |||
T73717 | CGAMP diammonium | ||
cGAMP (Cyclic GMP-AMPP) diammonium serves as an intrinsic second messenger in metazoans, initiating the production of interferons upon cytosolic DNA detection. It activates the stimulator of interferon genes (STING), sub... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00745 | IFN-alpha 2a/IFNA2 Protein, Human, Recombinant | Human | E. coli |
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common ... | |||
TMPJ-00746 | IFN-alpha 2b/IFNA2 Protein, Human, Recombinant | Human | E. coli |
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common ... | |||
TMPY-00007 | Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant | Mouse | P. pastoris (Yeast) |
Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 19.4 kDa and the accession number is B1AYH7. | |||
TMPY-00265 | Interferon alpha 2/IFNA2 Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
Interferon alpha 2/IFNA2 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 19.3 kDa and the accession number is P01563.1. | |||
TMPY-04799 | IFNAR2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPJ-00747 | IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant | Mouse | E. coli |
At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a c... | |||
TMPY-03735 | Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is B6CK11. | |||
TMPY-00096 | Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant | Rhesus | P. pastoris (Yeast) |
Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant is expressed in yeast. The predicted molecular weight is 19.5 kDa and the accession number is B6CK11. | |||
TMPY-02661 | Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P01573. | |||
TMPY-03319 | Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc) | Rhesus | HEK293 Cells |
Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.9 kDa and the accession number is B6CK11. | |||
TMPY-06407 | Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.29 kDa and the accession number is P01563-1. | |||
TMPY-00139 | IFNAR2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
IFNAR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is XP_005548871.1. | |||
TMPY-01640 | IFNAR2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1. | |||
TMPY-01642 | IFNAR2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPJ-00331 | IFNAR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-... | |||
TMPK-01017 | B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) | Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s... | |||
TMPK-01018 | B7-H3 Protein, Human, Recombinant (aa 29-245, His) | Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s... | |||
TMPK-01016 | B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled | Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s... | |||
TMPY-02841 | Fragilis/IFITM3 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interf... | |||
TMPJ-01206 | Sting Protein, Human, Recombinant (Sumo & His) | Human | E. coli |
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a ... | |||
TMPJ-01328 | ZBP1 Protein, Human, Recombinant (His) | Human | E. coli |
Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of vir... | |||
TMPY-03122 | GBP2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTP... | |||
TMPY-01775 | AIM2 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla... | |||
TMPY-00992 | ERAP2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum ... | |||
TMPY-04478 | IP6K1/IHPK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
IP6K1 (Inositol Hexakisphosphate Kinase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. IHPK1 is an inositol hexaphosphate kinase (IHPK) protein that belongs to the inositol phosph... | |||
TMPY-03612 | PSME1 Protein, Human, Recombinant (His) | Human | E. coli |
PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ... | |||
TMPY-03610 | PSME2 Protein, Human, Recombinant (His) | Human | E. coli |
PSME2, also known as PA28b, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ... | |||
TMPY-02887 | IFI30 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putat... | |||
TMPJ-00281 | CADM1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C... | |||
TMPY-00005 | FGF-8a Protein, Human, Recombinant | Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment... | |||
TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2. | |||
TMPY-00891 | Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) | Human | HEK293 Cells |
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2. | |||
TMPY-00871 | LAYN Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2. | |||
TMPY-00341 | FGFR3 Protein, Human, Recombinant (alpha IIIb, His) | Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2. | |||
TMPY-05288 | PLGF/PGF Protein, Human, Recombinant (aa 19-149) | Human | E. coli |
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2. | |||
TMPY-04116 | KRAS Protein,Human,Recombinant(G12C & Q61H, His) | Human | E. coli |
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2. | |||
TMPY-00748 | Nectin-2 Protein, Human, Recombinant | Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2. | |||
TMPY-00850 | ST2/IL-1 RL1 Protein, Human, Recombinant | Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2. | |||
TMPY-02792 | GDNF Protein, Human, Recombinant (HEK293) | Human | HEK293 Cells |
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2. | |||
TMPY-01691 | Clusterin Protein, Human, Recombinant (CLU34, His) | Human | HEK293 Cells |
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2. | |||
TMPY-00849 | ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2. | |||
TMPY-02011 | CD96 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2. | |||
TMPJ-00850 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) | Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPY-01985 | CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2. | |||
TMPY-05427 | CD19 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2. | |||
TMPY-02820 | SDF-1 Protein, Human, Recombinant (isoform a) | Human | E. coli |
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2. | |||
TMPJ-00335 | TGFBR2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2. | |||
TMPY-04113 | KRAS Protein,Human,Recombinant(G12D & Q61H, His) | Human | E. coli |
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2. | |||
TMPY-04844 | BTN3A1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2. | |||
TMPY-00751 | TrkB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2. | |||
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